Lex Luthor allied himself with Darkseid to invade earth. After Superman and The Justice League defeat Darkseid and his forces, Superman thwarts Darkseid's escape plans by blasting him with his heat vision. Superman takes Luthor to the authorities. Luthor escaped and travels to the Mortal Kombat universe, where he confronts Jax Briggs who defeats him in combat and imprisons him with Catwoman who was defeated by Sonya Blade previously. Luthor and Catwoman managed to make their getaway and traveled to Oa, where Luthor confronts Green Lantern who defeats him in battle. After the battle, Green Lantern, Luthor and Catwoman work together, Green Lantern drops Luthor and Catwoman off at Metropolis while Green Lantern goes to find the source of the world merge. With The Justice League's hands full, Luthor and Catwoman decide to band together the Injustice gang to save Earth. They recruit Deathstroke and The Joker, who were defeated by Scorpion and Sub-Zero, to their team. The Injustice gang soon runs into Captain Marvel and Superman.
Captain Marvel tells Superman and the Injustice gang that Darkseid has merged with another powerful being and became Dark Kahn. While Luthor sends Deathstroke and Joker to invade the enemies base, he and Catwoman go to the base where they were first held captive and are confronted by Scorpion and Sub-Zero. Sub-Zero freezes them both to the ground but Luthor, fueled by Kombat Rage, breaks himself free and defeats both Sub-Zero and Scorpion. Luthor frees Catwoman and they go to Jax's hanger bay. Catwoman does reconnaissance while Luthor goes after portal technology that belongs to the Mortal Kombat universe and is confronted by Jax once again and the two face off. After Luthor defeats Jax, Flash knocks Catwoman unconcious and attacks Luthor. The two fight and Luthor defeats Flash. The Justice League and The Injustice League arrive at Jax's hanger bay and use his portal technology to go to Merged Apokolips/Outworld to confront Dark Kahn.
He is defeated by Superman when both of them are overcome by the Kombat Rage. Superman was about to kill Luthor but was stopped by Batman who fought and was defeated by Superman. Once Superman overcomes The Kombat Rage, he goes to confront Dark Kahn, but is halted by Raiden, who Superman defeats and also aids Superman in destroying Dark Kahn.
- This version of the character is exclusive to the continuity of the video game Mortal Kombat vs. DC Universe and is an adaptation of Luthor. The original character was created by Jerry Siegel and Joe Shuster and first appeared in Superman #4.
- 2 Appearances of Alexander Luthor (Mortal Kombat vs. DC Universe)
- 1 Images featuring Alexander Luthor (Mortal Kombat vs. DC Universe)
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- Character Gallery: Alexander Luthor (Mortal Kombat vs. DC Universe)