Mandrake began as a stockbroker before he was eventually put under Poison Ivy's control early in the villain's career. Mandrake was kept under her poisonous spell for three months before being released, in that time having his physiology develop, giving him the power to make people in his vicinity sick using only his mind.
Resenting Batman for causing super villains like Poison Ivy to exist, Mister Noxious became a founding member of the Victim Syndicate and invaded a police gala at FoxTech to begin the crusade against "heroic" vigilantes.
- Unique Physiology
- 7 Appearances of Guy Mandrake (Prime Earth)
- 3 Images featuring Guy Mandrake (Prime Earth)
- Quotations by or about Guy Mandrake (Prime Earth)
- Character Gallery: Guy Mandrake (Prime Earth)