The Isis Foundation was an organization run by Lana Lang.
Officially a non profit organization, dedicated to offer support to the meteor infected. In truth, Lana Lang had founded the Isis Foundation as a cover her surveillance and investigations into her ex-husband, Lex Luthor.
After Lana was attacked by Brainiac and put in a coma, Chloe Sullivan assumed control of the Isis Foundation. During this time, Oliver Queen began using the foundation's building as a warehouse, for his team's equipment. The team adopted the Isis Foundation as their base, during their search for Chloe and Clark Kent.
Upon her return, Chloe started to use the foundation to counsel meteor infected teenagers. Chloe seemingly ended the foundation's normal operations, after she devoted herself full-time to the team. The Isis Foundation building was later abandoned in favor of Watchtower.
- 31 Appearances of Isis Foundation (Smallville)
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- Organization Gallery: Isis Foundation (Smallville)