Mariko Tamaki was born in Toronto, Ontario. She is of mixed Japanese Canadian and Jewish Canadian descent. Mariko attended Havergal College, an all girls' secondary school. She studied English literature at McGill University, graduating in 1994.
Mariko Tamaki is a Toronto writer, playwright, activist and performer. She has performed across Canada and the United States with fat activists Pretty Porky and Pissed Off and the theatre troupe TOA.
Tamaki has written a number of novels and short story collections, including Cover Me, True Lies: The Book of Bad Advice, Fake ID, (You) Set Me On Fire and Saving Montgomery Sole. She has collaborated with her cousin, artist Jillian Tamaki, on two award-winning graphic novels, Skim (2008) and This One Summer (2014).
As of December 2016, Tamaki was writing a new Hulk series starring Jennifer Walters for Marvel Comics, Tomb Raider for Dark Horse Comics and Supergirl: Being Super for DC.