The Mona Lisa is one of the most famous paintings by 16th Century artist and scientist Leonardo da Vinci.
History
New Earth
When his usual model fell ill, he was fortunate enough to find a new one in Michelle Carter of the 25th Century. Unfortunately, he was unable to sketch her when she had to leave for Rome with her brother. Luckily, Da Vinci was able to capture Michelle's unique look by memory with some subtle changes.[1]
Leonardo didn't sell the painting but was sold after his death by his assistants, switching from owner to owner until it got displayed at the Louvre, at Paris. There it would become a world treasure and thus a target for villains that tried to obtain it. One of these was Vandal Savage. [citation needed]
Teen Titans Go!
While the Titans appreciated "real art", Beast Boy and Cyborg theorized that Da Vinci had secretly hidden a code within the Mona Lisa. Using evidence such as the model's lack of eyebrows and greenish skin, the Titans alleged that the woman featured in the Mona Lisa was actually an alien, though Starfire questioned why this would be a problem because she herself was an alien to Earth too.
Upon being beamed into the painting by Rainbow Raider, the Titans discovered that the Mona Lisa was an alien and had her own UFO she kept under the bridge in the painting. [2]