In 1957, the newly-formed European Economic Community established the Dome, a supra-national police organization. At some later point Doctor Mist formed the Global Guardians to serve as a task force for the Dome.
Decades later, the Dome lost its funding when, in part because of the political machinations of Dr. Klaus Cornelius, the United Nations decided to close the Dome and instead fund the new Justice League International. The Global Guardians then fractured with Doctor Mist and his assistant Belphegor disappearing. Queen Bee of Bialya rebuilt the Dome in her country. She then brainwashed many of the former Global Guardians into her service and created an android Doctor Mist to lead the team.
Later on, Doctor Mist reappeared and helped Guardian members Jack O'Lantern and Owlwoman escape Bialya. Doctor Mist recruited a team to free the rest of the Guardians from Bialya mind control and then reformed the Global Guardians, building a new Dome headquarters somewhere in the Pacific.
An eternal, Mist's physical body was slain by an ancient force. Nonetheless, he did turn up alive and seemingly well after the Zero Hour crisis. At this time, calling himself Maltis, he formed a new team of heroes known as the Leymen. The group was short-lived. Maltis' time on the team even shorter as he had a heart attack soon after the team formed. Later, he was seemingly killed after being thrown into a pool of acid by the evil Mordru.
- Doctor Mist first appeared in Super Friends continuity in Super Friends #12 by E. Nelson Bridwell and Ramona Fradon. He was introduced in mainstream continuity in DC Comics Presents #46 by E. Nelson Bridwell and Alex Saviuk.
- Although this character was originally introduced during DC's Earth-One era of publication, their existence following the events of the 1985–86 limited series Crisis on Infinite Earths remains intact. However, some elements of the character's Pre-Crisis history may have been altered or removed for Post-Crisis New Earth continuity, and should be considered apocryphal.
- The concepts of the ancient kingdom of Kor and the Pillar of Life are taken from the novel She by H. Rider Haggard. Doctor Mist may be the character Noot from Wisdom's Daughter (a sequel to She), but this was only hinted at, never confirmed.
- An adaptation of She appeared in New Comics #6–22.
- Doctor Mist is also known as Ashos, Joab, Korathma, Samson, Mister Mystery, and Brother Mist.
- 35 Appearances of Nommo (New Earth)
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