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Reign is a powerful alien enemy of Supergirl. She is a Worldkiller, an alien embryo genetically modified and grown in a clandestine Kryptonian laboratory. Reign is gifted with super-human strength, speed and endurance, and is an adept swordswoman and hand-to-hand fighter.

Reign was created by Michael Green, Mike Johnson and Mahmud Asrar, first appearing in Supergirl (Volume 6) #5. (2012)

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